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Lineage-selective super enhancers mediate core regulatory circuitry during adipogenic and osteogenic differentiation of human mesenchymal stem cells

Human mesenchymal stem cells (hMSCs) can be differentiated into osteoblasts and adipocytes. During these processes, super enhancers (SEs) play important roles. Here, we performed comprehensive characterization of the SEs changes associated with adipogenic and osteogenic differentiation of hMSCs, and...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Tian, Wen, Hu, Shou-Ye, Di, Chen-Xi, He, Chang-Yi, Cao, Qi-Long, Hao, Ruo-Han, Dong, Shan-Shan, Liu, Cong-Cong, Rong, Yu, Kang, Hua-Feng, Yang, Tie-Lin, Yang, Zhi, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556616/
https://www.ncbi.nlm.nih.gov/pubmed/36224171
http://dx.doi.org/10.1038/s41419-022-05309-3