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NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

Combination therapies or multi-targeted drugs have been pointed out as an option to prevent the emergence of resistant clones, which could make long-term treatment more effective and translate into better clinical outcomes for cancer patients. The NT157 compound is a synthetic tyrphostin that leads...

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Detalles Bibliográficos
Autores principales: de Miranda, Lívia Bassani Lins, Lima, Keli, Coelho-Silva, Juan Luiz, Traina, Fabiola, Kobayashi, Susumu S., Machado-Neto, João Agostinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556623/
https://www.ncbi.nlm.nih.gov/pubmed/36224313
http://dx.doi.org/10.1038/s41598-022-21419-6