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Comparative efficacy and safety of JAK inhibitors as monotherapy and in combination with methotrexate in patients with active rheumatoid arthritis: A systematic review and meta-analysis

BACKGROUND: We aim to evaluate the efficacy and tolerability of Janus kinase inhibitors (JAKi) as monotherapy and in combination with methotrexate (MTX) in active rheumatoid arthritis (RA). METHODS: Medline, EMBASE, and Cochrane Library were systematically searched to identify relevant randomized co...

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Detalles Bibliográficos
Autores principales: Liu, Li, Yan, Yi-Dan, Shi, Fang-Hong, Lin, Hou-Wen, Gu, Zhi-Chun, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556706/
https://www.ncbi.nlm.nih.gov/pubmed/36248913
http://dx.doi.org/10.3389/fimmu.2022.977265