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Reduced humoral response to a third dose (booster) of SARS-CoV-2 mRNA vaccines by concomitant methotrexate therapy in elderly patients with rheumatoid arthritis

BACKGROUND: Several health authorities recommend a third (booster) vaccination to protect patients with rheumatic and musculoskeletal diseases from severe COVID-19. Methotrexate has been shown to reduce the efficacy of the first and second dose of SARS-CoV-2 mRNA vaccines. So far, it remains unknown...

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Detalles Bibliográficos
Autores principales: Stahl, David, tho Pesch, Carola, Brück, Carolin, Esser, Ruth L, Thiele, Jan, Di Cristanziano, Veronica, Kofler, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556739/
https://www.ncbi.nlm.nih.gov/pubmed/36216409
http://dx.doi.org/10.1136/rmdopen-2022-002632