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Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution

Atherogenesis involves an interplay of inflammation, tissue remodeling and cellular transdifferentiation (CTD), making it especially difficult to precisely delineate its pathophysiology. Here we use single-cell RNA sequencing and systems-biology approaches to analyze the transcriptional profiles of...

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Detalles Bibliográficos
Autores principales: Alsaigh, Tom, Evans, Doug, Frankel, David, Torkamani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556750/
https://www.ncbi.nlm.nih.gov/pubmed/36224302
http://dx.doi.org/10.1038/s42003-022-04056-7