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Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution
Atherogenesis involves an interplay of inflammation, tissue remodeling and cellular transdifferentiation (CTD), making it especially difficult to precisely delineate its pathophysiology. Here we use single-cell RNA sequencing and systems-biology approaches to analyze the transcriptional profiles of...
Autores principales: | Alsaigh, Tom, Evans, Doug, Frankel, David, Torkamani, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556750/ https://www.ncbi.nlm.nih.gov/pubmed/36224302 http://dx.doi.org/10.1038/s42003-022-04056-7 |
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