A conserved loop sequence of the proteasome system depupylase Dop regulates substrate selectivity in Mycobacterium tuberculosis

Mycobacteria use a proteasome system that is similar to a eukaryotic proteasome but do not use ubiquitin to target proteins for degradation. Instead, mycobacteria encode a prokaryotic ubiquitin-like protein (Pup) that posttranslationally modifies proteins to mark them for proteolysis. Pupylation occ...

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Detalles Bibliográficos
Autores principales: Yoo, Jin Hee, Kahne, Shoshanna C., Darwin, K. Heran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556782/
https://www.ncbi.nlm.nih.gov/pubmed/36100038
http://dx.doi.org/10.1016/j.jbc.2022.102478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556782/
https://www.ncbi.nlm.nih.gov/pubmed/36100038
http://dx.doi.org/10.1016/j.jbc.2022.102478

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