Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery

The NtrC family of proteins senses external stimuli and accordingly stimulates stress and virulence pathways via activation of associated σ(54)-dependent RNA polymerases. However, the structural determinants that mediate this activation are not well understood. Here, we establish using computational...

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Detalles Bibliográficos
Autores principales: Singh, Jayanti, Sahil, Mohammad, Ray, Shamayeeta, Dcosta, Criss, Panjikar, Santosh, Krishnamoorthy, G., Mondal, Jagannath, Anand, Ruchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556785/
https://www.ncbi.nlm.nih.gov/pubmed/35988639
http://dx.doi.org/10.1016/j.jbc.2022.102399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556785/
https://www.ncbi.nlm.nih.gov/pubmed/35988639
http://dx.doi.org/10.1016/j.jbc.2022.102399

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