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Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery
The NtrC family of proteins senses external stimuli and accordingly stimulates stress and virulence pathways via activation of associated σ(54)-dependent RNA polymerases. However, the structural determinants that mediate this activation are not well understood. Here, we establish using computational...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556785/ https://www.ncbi.nlm.nih.gov/pubmed/35988639 http://dx.doi.org/10.1016/j.jbc.2022.102399 |