Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets

Amyloid protein aggregation is commonly associated with progressive neurodegenerative diseases, however not all amyloid fibrils are pathogenic. The neuronal cytoplasmic polyadenylation element binding protein is a regulator of synaptic mRNA translation and has been shown to form functional amyloid a...

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Detalles Bibliográficos
Autores principales: Bowler, Jeannette T., Sawaya, Michael R., Boyer, David R., Cascio, Duilio, Bali, Manya, Eisenberg, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556795/
https://www.ncbi.nlm.nih.gov/pubmed/35988647
http://dx.doi.org/10.1016/j.jbc.2022.102396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556795/
https://www.ncbi.nlm.nih.gov/pubmed/35988647
http://dx.doi.org/10.1016/j.jbc.2022.102396

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