Vertical sleeve gastrectomy normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

OBJECTIVES: Glucocorticoids produced by the adrenal cortex are essential for the maintenance of metabolic homeostasis. Glucocorticoid activation is catalysed by 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). Excess glucocorticoids are associated with insulin resistance and hyperglycaemia. A small nu...

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Detalles Bibliográficos
Autores principales: Akalestou, Elina, Lopez-Noriega, Livia, Christakis, Ioannis, Hu, Ming, Miras, Alexander D., Leclerc, Isabelle, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556837/
https://www.ncbi.nlm.nih.gov/pubmed/36246869
http://dx.doi.org/10.3389/fendo.2022.1020576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556837/
https://www.ncbi.nlm.nih.gov/pubmed/36246869
http://dx.doi.org/10.3389/fendo.2022.1020576

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