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DCAF7 regulates cell proliferation through IRS1-FOXO1 signaling

Cell proliferation is dependent on growth factors insulin and IGF1. We sought to identify interactors of IRS1, the most proximal mediator of insulin/IGF1 signaling, that regulate cell proliferation. Using proximity-dependent biotin identification (BioID), we detected 40 proteins displaying proximal...

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Detalles Bibliográficos
Autores principales: Frendo-Cumbo, Scott, Li, Taoyingnan, Ammendolia, Dustin A., Coyaud, Etienne, Laurent, Estelle M.N., Liu, Yuan, Bilan, Philip J., Polevoy, Gordon, Raught, Brian, Brill, Julie A., Klip, Amira, Brumell, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556925/
https://www.ncbi.nlm.nih.gov/pubmed/36248734
http://dx.doi.org/10.1016/j.isci.2022.105188