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Natural products targeting human lactate dehydrogenases for cancer therapy: A mini review

Reprogramming cancer metabolism has become the hallmark of cancer progression. As the key enzyme catalyzing the conversion of pyruvate to lactate in aerobic glycolysis of cancer cells, human lactate dehydrogenase (LDH) has been a promising target in the discovery of anticancer agents. Natural produc...

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Detalles Bibliográficos
Autores principales: Yao, Huankai, Yang, Feng, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556992/
https://www.ncbi.nlm.nih.gov/pubmed/36247675
http://dx.doi.org/10.3389/fchem.2022.1013670