The protease DDI2 regulates NRF1 activation in response to cadmium toxicity

DNA-damage inducible 1 homolog 2 (DDI2) is a protease that activates the transcription factor NRF1. Cellular models have shown that this pathway contributes to cell-stress adaptation, for example, on proteasome inhibition. However, DDI2 physiological function is unknown. Ddi2 Knock-out (KO) mice wer...

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Detalles Bibliográficos
Autores principales: Ribeiro, Sérgio T., de Gassart, Aude, Bettigole, Sarah, Zaffalon, Lea, Chavarria, Claire, Op, Melanie, Nugraha, Kalvin, Martinon, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557025/
https://www.ncbi.nlm.nih.gov/pubmed/36248746
http://dx.doi.org/10.1016/j.isci.2022.105227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557025/
https://www.ncbi.nlm.nih.gov/pubmed/36248746
http://dx.doi.org/10.1016/j.isci.2022.105227

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