Cargando…

Cooperative RNA degradation stabilizes intermediate epithelial-mesenchymal states and supports a phenotypic continuum

Multiple intermediate epithelial-mesenchymal transition (EMT) states reflecting hybrid epithelial and mesenchymal phenotypes were observed in physiological and pathological conditions. Previous theoretical models explaining multiple EMT states rely on regulatory loops involving transcriptional feedb...

Descripción completa

Detalles Bibliográficos
Autores principales: Nordick, Benjamin, Chae-Yeon Park, Mary, Quaranta, Vito, Hong, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557027/
https://www.ncbi.nlm.nih.gov/pubmed/36248730
http://dx.doi.org/10.1016/j.isci.2022.105224