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Cooperative RNA degradation stabilizes intermediate epithelial-mesenchymal states and supports a phenotypic continuum
Multiple intermediate epithelial-mesenchymal transition (EMT) states reflecting hybrid epithelial and mesenchymal phenotypes were observed in physiological and pathological conditions. Previous theoretical models explaining multiple EMT states rely on regulatory loops involving transcriptional feedb...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557027/ https://www.ncbi.nlm.nih.gov/pubmed/36248730 http://dx.doi.org/10.1016/j.isci.2022.105224 |