Seed- and leaf-based expression of FGF21-transferrin fusion proteins for oral delivery and treatment of non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is a global disease with no effective medication. The fibroblast growth factor 21 (FGF21) can reverse this liver dysfunction, but requires targeted delivery to the liver, which can be achieved via oral administration. Therefore, we fused FGF21 to transferrin (Tf)...

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Detalles Bibliográficos
Autores principales: Hou, Hsuan-Wu, Bishop, Christopher A., Huckauf, Jana, Broer, Inge, Klaus, Susanne, Nausch, Henrik, Buyel, Johannes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557105/
https://www.ncbi.nlm.nih.gov/pubmed/36247628
http://dx.doi.org/10.3389/fpls.2022.998596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557105/
https://www.ncbi.nlm.nih.gov/pubmed/36247628
http://dx.doi.org/10.3389/fpls.2022.998596

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