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Two subtypes of cutaneous melanoma with distinct mutational signatures and clinico-genomic characteristics

Background: To decipher mutational signatures and their associations with biological implications in cutaneous melanomas (CMs), including those with a low ultraviolet (UV) signature. Materials and Methods: We applied non-negative matrix factorization (NMF) and unsupervised clustering to the 96-class...

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Detalles Bibliográficos
Autores principales: Kim, Yoon-Seob, Lee, Minho, Chung, Yeun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557124/
https://www.ncbi.nlm.nih.gov/pubmed/36246650
http://dx.doi.org/10.3389/fgene.2022.987205