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Two subtypes of cutaneous melanoma with distinct mutational signatures and clinico-genomic characteristics
Background: To decipher mutational signatures and their associations with biological implications in cutaneous melanomas (CMs), including those with a low ultraviolet (UV) signature. Materials and Methods: We applied non-negative matrix factorization (NMF) and unsupervised clustering to the 96-class...
Autores principales: | Kim, Yoon-Seob, Lee, Minho, Chung, Yeun-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557124/ https://www.ncbi.nlm.nih.gov/pubmed/36246650 http://dx.doi.org/10.3389/fgene.2022.987205 |
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