Synthesis of the cyanobacterial halometabolite Chlorosphaerolactylate B and demonstration of its antimicrobial effect in vitro and in vivo

Chlorosphaerolactylate B, a newly discovered antimicrobial halometabolite from the cyanobacterium Sphaerospermopsis sp. LEGE 00249 has been synthesized in three steps by using 12-bromododecanoic acid as starting material. A total of 0.5 g was produced for in vitro and in vivo antimicrobial efficacy...

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Detalles Bibliográficos
Autores principales: Jensen, Nikoline, Jensen, Henrik Elvang, Aalbaek, Bent, Blirup-Plum, Sophie Amalie, Soto, Sara M., Cepas, Virginio, López, Yuly, Gabasa, Yaiza, Gutiérrez-del-Río, Ignacio, Villar, Claudio J., Lombó, Felipe, Iglesias, María José, Soengas, Raquel, López Ortiz, Fernando, Jensen, Louise Kruse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557163/
https://www.ncbi.nlm.nih.gov/pubmed/36246241
http://dx.doi.org/10.3389/fmicb.2022.950855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557163/
https://www.ncbi.nlm.nih.gov/pubmed/36246241
http://dx.doi.org/10.3389/fmicb.2022.950855

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