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An expanded population of CD8(dim) T cells with features of mitochondrial dysfunction and senescence is associated with persistent HIV-associated Kaposi’s sarcoma under ART

HIV-associated Kaposi’s sarcoma (KS), which is caused by Kaposi’s sarcoma-associated herpesvirus, usually arises in the context of uncontrolled HIV replication and immunosuppression. However, disease occasionally occurs in individuals with durable HIV viral suppression and CD4 T cell recovery under...

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Detalles Bibliográficos
Autores principales: Clutton, Genevieve T., Weideman, Ann Marie K., Goonetilleke, Nilu P., Maurer, Toby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557199/
https://www.ncbi.nlm.nih.gov/pubmed/36247006
http://dx.doi.org/10.3389/fcell.2022.961021