Cargando…

Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure

OBJECTIVE: Disturbances in NAD(+) metabolism have been described as a hallmark for multiple metabolic and age-related diseases, including type 2 diabetes. While alterations in pancreatic β-cell function are critical determinants of whole-body glucose homeostasis, the role of NAD(+) metabolism in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Cercillieux, Angelique, Ratajczak, Joanna, Joffraud, Magali, Sanchez-Garcia, José Luis, Jacot, Guillaume, Zollinger, Alix, Métairon, Sylviane, Giroud-Gerbetant, Judith, Rumpler, Marie, Ciarlo, Eleonora, Valera-Alberni, Miriam, Sambeat, Audrey, Canto, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557729/
https://www.ncbi.nlm.nih.gov/pubmed/36165811
http://dx.doi.org/10.1016/j.molmet.2022.101605