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Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure
OBJECTIVE: Disturbances in NAD(+) metabolism have been described as a hallmark for multiple metabolic and age-related diseases, including type 2 diabetes. While alterations in pancreatic β-cell function are critical determinants of whole-body glucose homeostasis, the role of NAD(+) metabolism in the...
Autores principales: | Cercillieux, Angelique, Ratajczak, Joanna, Joffraud, Magali, Sanchez-Garcia, José Luis, Jacot, Guillaume, Zollinger, Alix, Métairon, Sylviane, Giroud-Gerbetant, Judith, Rumpler, Marie, Ciarlo, Eleonora, Valera-Alberni, Miriam, Sambeat, Audrey, Canto, Carles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557729/ https://www.ncbi.nlm.nih.gov/pubmed/36165811 http://dx.doi.org/10.1016/j.molmet.2022.101605 |
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