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Spectral imaging and nucleic acid mimics fluorescence in situ hybridization (SI-NAM-FISH) for multiplex detection of clinical pathogens

The application of nucleic acid mimics (NAMs), such as locked nucleic acid (LNA) and 2′-O-methyl-RNA (2’OMe), has improved the performance of fluorescence in situ hybridization (FISH) methods for the detection/location of clinical pathogens since they provide design versatility and thermodynamic con...

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Detalles Bibliográficos
Autores principales: Azevedo, Andreia S., Fernandes, Ricardo M., Faria, Ana R., Silvestre, Oscar F., Nieder, Jana B., Lou, Chenguang, Wengel, Jesper, Almeida, Carina, Azevedo, Nuno F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557775/
https://www.ncbi.nlm.nih.gov/pubmed/36246234
http://dx.doi.org/10.3389/fmicb.2022.976639