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Exocrine and Endocrine Inflammation Increases Cellular Replication in the Pancreatic Duct Compartment in Type 1 Diabetes

CONTEXT: We recently demonstrated increased cellular proliferation in the pancreatic ductal gland (PDG) compartment of organ donors with type 1 diabetes, suggesting that PDGs may harbor progenitor cells capable of pancreatic regeneration. OBJECTIVE: We evaluated the impact of diabetes and pancreatic...

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Detalles Bibliográficos
Autores principales: Kulkarni, Shweta, Posgai, Amanda L, Kusmartseva, Irina, Wasserfall, Clive H, Atkinson, Mark A, Butler, Alexandra E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557836/
https://www.ncbi.nlm.nih.gov/pubmed/36249412
http://dx.doi.org/10.1210/jendso/bvac136