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Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression–body mass index genetic risk score interactions

BACKGROUND: Depression and obesity are complex global health problems. Recent studies suggest that a genetic predisposition to obesity might be accentuated in people with depression, but these analyses are prone to bias. Here, we tested the hypothesis that depression accentuates genetic susceptibili...

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Detalles Bibliográficos
Autores principales: Casanova, Francesco, O’Loughlin, Jessica, Lewis, Cathryn, Frayling, Timothy M, Wood, Andrew R, Tyrrell, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557895/
https://www.ncbi.nlm.nih.gov/pubmed/35388897
http://dx.doi.org/10.1093/ije/dyac052