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The Influenza-Induced Pulmonary Inflammatory Exudate in Susceptible Tpl2-Deficient Mice Is Dictated by Type I IFN Signaling
The most prominent host response to viral infection is the production of type 1 interferons (T1 IFNs). One host regulator of the T1 IFNs is the serine-threonine kinase, tumor progression locus 2 (TPL2). We have previously demonstrated that Tpl2(−/−) mice succumb to infection with a low-pathogenicity...
Autores principales: | Latha, Krishna, Patel, Yesha, Rao, Sanjana, Watford, Wendy T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558022/ https://www.ncbi.nlm.nih.gov/pubmed/36227523 http://dx.doi.org/10.1007/s10753-022-01736-8 |
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