Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation

Protein S-acylation is a reversible post-translational modification that modulates the localization and function of many cellular proteins. S-acylation is mediated by a family of zinc finger DHHC (Asp-His-His-Cys) domain–containing (zDHHC) proteins encoded by 23 distinct ZDHHC genes in the human gen...

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Detalles Bibliográficos
Autores principales: Salaun, Christine, Takizawa, Hiroya, Galindo, Alex, Munro, Kevin R., McLellan, Jayde, Sugimoto, Isamu, Okino, Tomotaka, Tomkinson, Nicholas C.O., Chamberlain, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558053/
https://www.ncbi.nlm.nih.gov/pubmed/36087837
http://dx.doi.org/10.1016/j.jbc.2022.102469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558053/
https://www.ncbi.nlm.nih.gov/pubmed/36087837
http://dx.doi.org/10.1016/j.jbc.2022.102469

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