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Inferring Epistasis from Genetic Time-series Data

Epistasis refers to fitness or functional effects of mutations that depend on the sequence background in which these mutations arise. Epistasis is prevalent in nature, including populations of viruses, bacteria, and cancers, and can contribute to the evolution of drug resistance and immune escape. H...

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Detalles Bibliográficos
Autores principales: Sohail, Muhammad Saqib, Louie, Raymond H Y, Hong, Zhenchen, Barton, John P, McKay, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558069/
https://www.ncbi.nlm.nih.gov/pubmed/36130322
http://dx.doi.org/10.1093/molbev/msac199