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Inferring Epistasis from Genetic Time-series Data
Epistasis refers to fitness or functional effects of mutations that depend on the sequence background in which these mutations arise. Epistasis is prevalent in nature, including populations of viruses, bacteria, and cancers, and can contribute to the evolution of drug resistance and immune escape. H...
Autores principales: | Sohail, Muhammad Saqib, Louie, Raymond H Y, Hong, Zhenchen, Barton, John P, McKay, Matthew R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558069/ https://www.ncbi.nlm.nih.gov/pubmed/36130322 http://dx.doi.org/10.1093/molbev/msac199 |
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