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Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells

Exercise training is critical for the prevention and treatment of obesity, but its underlying mechanisms remain incompletely understood given the challenge of profiling heterogeneous effects across multiple tissues and cell types. Here, we address this challenge and opposing effects of exercise and...

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Detalles Bibliográficos
Autores principales: Yang, Jiekun, Vamvini, Maria, Nigro, Pasquale, Ho, Li-Lun, Galani, Kyriakitsa, Alvarez, Marcus, Tanigawa, Yosuke, Renfro, Ashley, Carbone, Nicholas P., Laakso, Markku, Agudelo, Leandro Z., Pajukanta, Päivi, Hirshman, Michael F., Middelbeek, Roeland J.W., Grove, Kevin, Goodyear, Laurie J., Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558082/
https://www.ncbi.nlm.nih.gov/pubmed/36198295
http://dx.doi.org/10.1016/j.cmet.2022.09.004