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Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity
Checkpoint control and immunomodulatory antibodies have become important tools for modulating tumor or self-reactive immune responses. A major issue preventing to make full use of the potential of these immunomodulatory antibodies are the severe side-effects, ranging from systemic cytokine release s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558126/ https://www.ncbi.nlm.nih.gov/pubmed/36248847 http://dx.doi.org/10.3389/fimmu.2022.970290 |