Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults

BACKGROUND:  Tryptophan (Trp) metabolites from intestinal bacteria (indole, indole acetic acid [IAA] and indole propionic acid [IPA]), and the Trp metabolite kynurenine (Kyn) from the indoleamine 2,3-dioxygenase (IDO) pathway, are aryl hydrocarbon receptor (AhR) agonists and thus, can regulate immun...

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Detalles Bibliográficos
Autores principales: Riazati, Niknaz, Kable, Mary E., Newman, John W., Adkins, Yuriko, Freytag, Tammy, Jiang, Xiaowen, Stephensen, Charles B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558171/
https://www.ncbi.nlm.nih.gov/pubmed/36248784
http://dx.doi.org/10.3389/fimmu.2022.917966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558171/
https://www.ncbi.nlm.nih.gov/pubmed/36248784
http://dx.doi.org/10.3389/fimmu.2022.917966

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