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Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults

BACKGROUND: Tryptophan (Trp) metabolites from intestinal bacteria (indole, indole acetic acid [IAA] and indole propionic acid [IPA]), and the Trp metabolite kynurenine (Kyn) from the indoleamine 2,3-dioxygenase (IDO) pathway, are aryl hydrocarbon receptor (AhR) agonists and thus, can regulate immun...

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Detalles Bibliográficos
Autores principales:	Riazati, Niknaz, Kable, Mary E., Newman, John W., Adkins, Yuriko, Freytag, Tammy, Jiang, Xiaowen, Stephensen, Charles B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558171/ https://www.ncbi.nlm.nih.gov/pubmed/36248784 http://dx.doi.org/10.3389/fimmu.2022.917966

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