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The role of GABA in islet function

Gamma aminobutyric acid (GABA) is a non-proteinogenic amino acid and neurotransmitter that is produced in the islet at levels as high as in the brain. GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD), of which the 65 kDa isoform (GAD65) is a major autoantigen in type 1 diabetes. O...

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Detalles Bibliográficos
Autores principales: Hagan, D. Walker, Ferreira, Sandra M., Santos, Gustavo J., Phelps, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558271/
https://www.ncbi.nlm.nih.gov/pubmed/36246925
http://dx.doi.org/10.3389/fendo.2022.972115