TCF7/SNAI2/miR-4306 feedback loop promotes hypertrophy of ligamentum flavum

BACKGROUND: Hypertrophy of ligamentum flavum (HLF) is the mainly cause of lumbar spinal stenosis (LSS), but the precise mechanism of HLF formation has not been fully elucidated. Emerging evidence indicates that transcription factor 7 (TCF7) is the key downstream functional molecule of Wnt/β-catenin...

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Detalles Bibliográficos
Autores principales: Duan, Yang, Li, Jianjun, Qiu, Sujun, Ni, Songjia, Cao, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558422/
https://www.ncbi.nlm.nih.gov/pubmed/36224570
http://dx.doi.org/10.1186/s12967-022-03677-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558422/
https://www.ncbi.nlm.nih.gov/pubmed/36224570
http://dx.doi.org/10.1186/s12967-022-03677-0

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