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TCF7/SNAI2/miR-4306 feedback loop promotes hypertrophy of ligamentum flavum
BACKGROUND: Hypertrophy of ligamentum flavum (HLF) is the mainly cause of lumbar spinal stenosis (LSS), but the precise mechanism of HLF formation has not been fully elucidated. Emerging evidence indicates that transcription factor 7 (TCF7) is the key downstream functional molecule of Wnt/β-catenin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558422/ https://www.ncbi.nlm.nih.gov/pubmed/36224570 http://dx.doi.org/10.1186/s12967-022-03677-0 |