SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia

RATIONALE: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 pneumonia. We hypothesize that SARS-CoV-2 causes alveolar injury and hypoxemia by damaging mitochondria in airway epithelial cells (AEC) and pulmonary artery smooth muscle cells (PASMC), triggering apoptosis and...

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Detalles Bibliográficos
Autores principales: Archer, Stephen L., Dasgupta, Asish, Chen, Kuang-Hueih, Wu, Danchen, Baid, Kaushal, Mamatis, John E., Gonzalez, Victoria, Read, Austin, Bentley, Rachel ET., Martin, Ashley Y., Mewburn, Jeffrey D., Dunham-Snary, Kimberly J., Evans, Gerald A., Levy, Gary, Jones, Oliver, Al-Qazazi, Ruaa, Ring, Brooke, Alizadeh, Elahe, Hindmarch, Charles CT., Rossi, Jenna, Lima, Patricia DA., Falzarano, Darryl, Banerjee, Arinjay, Colpitts, Che C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558649/
https://www.ncbi.nlm.nih.gov/pubmed/36334378
http://dx.doi.org/10.1016/j.redox.2022.102508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558649/
https://www.ncbi.nlm.nih.gov/pubmed/36334378
http://dx.doi.org/10.1016/j.redox.2022.102508

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