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Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly

The stimulation of autophagy or lysosomes has been considered therapeutic for neurodegenerative disorders because the accumulation of misfolded proteins is commonly observed in the brains of individuals with these diseases. Although zinc is known to play critical roles in the functions of lysosomes...

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Detalles Bibliográficos
Autores principales: Kim, Ki-Ryeong, Park, Sang Eun, Hong, Ji-Ye, Koh, Jae-Young, Cho, Dong-Hyung, Hwang, Jung Jin, Kim, Yang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558701/
https://www.ncbi.nlm.nih.gov/pubmed/36246521
http://dx.doi.org/10.3389/fncel.2022.895750