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Do bisphosphonates and RANKL inhibitors alter the progression of coronary artery calcification? A systematic review and meta-analysis protocol

INTRODUCTION: Whether bisphosphonates and RANKL inhibitors play a novel role in delaying cardiovascular calcification is unknown. Their action on regulatory enzymes in the mevalonic acid pathway, which is implicated in both bone and lipid metabolism, may be a novel therapeutic target to manage coron...

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Detalles Bibliográficos
Autores principales: Saunders, Samantha Louise, Chaudhri, Kanika, McOrist, Nathan Scott, Gnanenthiran, Sonali R, Shalaby, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558804/
https://www.ncbi.nlm.nih.gov/pubmed/36207048
http://dx.doi.org/10.1136/bmjopen-2022-066255