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Do bisphosphonates and RANKL inhibitors alter the progression of coronary artery calcification? A systematic review and meta-analysis protocol
INTRODUCTION: Whether bisphosphonates and RANKL inhibitors play a novel role in delaying cardiovascular calcification is unknown. Their action on regulatory enzymes in the mevalonic acid pathway, which is implicated in both bone and lipid metabolism, may be a novel therapeutic target to manage coron...
Autores principales: | Saunders, Samantha Louise, Chaudhri, Kanika, McOrist, Nathan Scott, Gnanenthiran, Sonali R, Shalaby, Grant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558804/ https://www.ncbi.nlm.nih.gov/pubmed/36207048 http://dx.doi.org/10.1136/bmjopen-2022-066255 |
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