Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study

Progressive dilation of the infrarenal aortic diameter is a consequence of the ageing process and is considered the main determinant of abdominal aortic aneurysm (AAA). We aimed to investigate the genetic and clinical determinants of abdominal aortic diameter (AAD). We conducted a meta-analysis of g...

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Detalles Bibliográficos
Autores principales: Portilla-Fernandez, Eliana, Klarin, Derek, Hwang, Shih-Jen, Biggs, Mary L, Bis, Joshua C, Weiss, Stefan, Rospleszcz, Susanne, Natarajan, Pradeep, Hoffmann, Udo, Rogers, Ian S, Truong, Quynh A, Völker, Uwe, Dörr, Marcus, Bülow, Robin, Criqui, Michael H, Allison, Matthew, Ganesh, Santhi K, Yao, Jie, Waldenberger, Melanie, Bamberg, Fabian, Rice, Kenneth M, Essers, Jeroen, Kapteijn, Daniek M C, van der Laan, Sander W, de Knegt, Rob J, Ghanbari, Mohsen, Felix, Janine F, Ikram, M Arfan, Kavousi, Maryam, Uitterlinden, Andre G, Roks, Anton J M, Danser, A H Jan, Tsao, Philip S, Damrauer, Scott M, Guo, Xiuqing, Rotter, Jerome I, Psaty, Bruce M, Kathiresan, Sekar, Völzke, Henry, Peters, Annette, Johnson, Craig, Strauch, Konstantin, Meitinger, Thomas, O’Donnell, Christopher J, Dehghan, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558840/
https://www.ncbi.nlm.nih.gov/pubmed/35234888
http://dx.doi.org/10.1093/hmg/ddac051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558840/
https://www.ncbi.nlm.nih.gov/pubmed/35234888
http://dx.doi.org/10.1093/hmg/ddac051

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