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Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is characterized by the presence of disease-specific autoreactive B cell responses, in particular those generating anti-citrullinated protein antibodies (ACPA). For many years, Epstein-Barr virus (EBV) has been implicated in disease pathogenesis, possibly by faci...

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Detalles Bibliográficos
Autores principales: Kroos, Sanne, Kampstra, Arieke S. B., Toes, René E. M., Slot, Linda M., Scherer, Hans U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559001/
https://www.ncbi.nlm.nih.gov/pubmed/36229887
http://dx.doi.org/10.1186/s13075-022-02919-2