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Estimating the effect size of a hidden causal factor between SNPs and a continuous trait: a mediation model approach
BACKGROUND: Observational studies and Mendelian randomization experiments have been used to identify many causal factors for complex traits in humans. Given a set of causal factors, it is important to understand the extent to which these causal factors explain some, all, or none of the genetic herit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559019/ https://www.ncbi.nlm.nih.gov/pubmed/36229773 http://dx.doi.org/10.1186/s12859-022-04977-4 |