A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies

Therapeutic monoclonal antibodies (mAbs) have a propensity to host a large number of chemical and enzymatical modifications that need to be properly assessed for their potential impact on target binding. Traditional strategies of assessing the criticality of these attributes often involve a laboriou...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengqi, Yan, Yuetian, Wang, Shunhai, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559042/
https://www.ncbi.nlm.nih.gov/pubmed/36224723
http://dx.doi.org/10.1080/19420862.2022.2133674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559042/
https://www.ncbi.nlm.nih.gov/pubmed/36224723
http://dx.doi.org/10.1080/19420862.2022.2133674

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