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TENAYA and LUCERNE: Rationale and Design for the Phase 3 Clinical Trials of Faricimab for Neovascular Age-Related Macular Degeneration

PURPOSE: To describe the design and rationale of the phase 3 TENAYA (ClinicalTrials.gov identifier, NCT03823287) and LUCERNE (ClinicalTrials.gov identifier, NCT03823300) trials that aimed to assess efficacy, safety, and durability of faricimab, the first bispecific antibody for intraocular use, whic...

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Detalles Bibliográficos
Autores principales: Khanani, Arshad M., Guymer, Robyn H., Basu, Karen, Boston, Heather, Heier, Jeffrey S., Korobelnik, Jean-François, Kotecha, Aachal, Lin, Hugh, Silverman, David, Swaminathan, Balakumar, Willis, Jeffrey R., Yoon, Young Hee, Quezada-Ruiz, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559073/
https://www.ncbi.nlm.nih.gov/pubmed/36246941
http://dx.doi.org/10.1016/j.xops.2021.100076