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Single-cell transcriptome analyses reveal distinct gene expression signatures of severe COVID-19 in the presence of clonal hematopoiesis

Clonal hematopoiesis of indeterminate potential (CHIP), a common aging-related process that predisposes individuals to various inflammatory responses, has been reported to be associated with COVID-19 severity. However, the immunological signature and the exact gene expression program by which the pr...

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Detalles Bibliográficos
Autores principales: Choi, Baekgyu, Kang, Chang Kyung, Park, Seongwan, Lee, Dohoon, Lee, Andrew J., Ko, Yuji, Kang, Suk-Jo, Kang, Kyuho, Kim, Sun, Koh, Youngil, Jung, Inkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559247/
https://www.ncbi.nlm.nih.gov/pubmed/36229591
http://dx.doi.org/10.1038/s12276-022-00866-1