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Controversies and Open Questions in Management of Cancer-Free Carriers of Germline Pathogenic Variants in BRCA1/BRCA2

SIMPLE SUMMARY: Female carriers of germline pathogenic/likely pathogenic variants (P/LPVs) in the BRCA1/BRCA2 (BRCA) genes are at a substantially increased lifetime risk for developing breast, ovarian, and (to a lesser extent) other cancer types. Multiple national and international surveillance guid...

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Detalles Bibliográficos
Autores principales: Bernstein-Molho, Rinat, Friedman, Eitan, Evron, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559251/
https://www.ncbi.nlm.nih.gov/pubmed/36230512
http://dx.doi.org/10.3390/cancers14194592