Pan-cancer analysis of AIM2 inflammasomes with potential implications for immunotherapy in human cancer: A bulk omics research and single cell sequencing validation

BACKGROUND: The absent in melanoma 2 (AIM2) inflammasome is a multi-protein platform that recognizes aberrant cytoplasmic double-stranded DNA(dsDNA) and induces cytokine maturation, release, and pyroptosis. Some studies found that the AIM2 inflammasome was a double-edged sword in many cancers. Howev...

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Detalles Bibliográficos
Autores principales: Qin, Yan, Pan, Liuxian, Qin, Tianyu, Ruan, Hanyi, Zhang, Yujie, Zhang, Yan, Li, Jianli, Yang, Jianrong, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559585/
https://www.ncbi.nlm.nih.gov/pubmed/36248785
http://dx.doi.org/10.3389/fimmu.2022.998266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559585/
https://www.ncbi.nlm.nih.gov/pubmed/36248785
http://dx.doi.org/10.3389/fimmu.2022.998266

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