Cargando…

Pan-cancer analysis of AIM2 inflammasomes with potential implications for immunotherapy in human cancer: A bulk omics research and single cell sequencing validation

BACKGROUND: The absent in melanoma 2 (AIM2) inflammasome is a multi-protein platform that recognizes aberrant cytoplasmic double-stranded DNA(dsDNA) and induces cytokine maturation, release, and pyroptosis. Some studies found that the AIM2 inflammasome was a double-edged sword in many cancers. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Yan, Pan, Liuxian, Qin, Tianyu, Ruan, Hanyi, Zhang, Yujie, Zhang, Yan, Li, Jianli, Yang, Jianrong, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559585/ https://www.ncbi.nlm.nih.gov/pubmed/36248785 http://dx.doi.org/10.3389/fimmu.2022.998266

Ejemplares similares

Pan-cancer analysis of IFN-γ with possible immunotherapeutic significance: a verification of single-cell sequencing and bulk omics research
por: Wei, Xiaoying, et al.
Publicado: (2023)

GIMAP7 as a Potential Predictive Marker for Pan-Cancer Prognosis and Immunotherapy Efficacy
por: Qin, Yan, et al.
Publicado: (2022)

Pan-cancer analysis identifies migrasome-related genes as a potential immunotherapeutic target: A bulk omics research and single cell sequencing validation
por: Qin, Yan, et al.
Publicado: (2022)

Pan-cancer analysis of NLRP3 inflammasome with potential implications in prognosis and immunotherapy in human cancer
por: Ju, Mingyi, et al.
Publicado: (2020)

Guanylate-Binding Protein 1 as a Potential Predictor of Immunotherapy: A Pan-Cancer Analysis
por: Zhao, Yaqi, et al.
Publicado: (2022)

Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response
por: Zhang, Zhen, et al.
Publicado: (2022)

Pan-cancer analyses of clinical prognosis, immune infiltration, and immunotherapy efficacy for TRPV family using multi-omics data
por: Shen, Chong, et al.
Publicado: (2023)

Inflammasome-independent functions of AIM2
por: Zhao, Junjie, et al.
Publicado: (2021)

Comprehensive Pan-Cancer Analysis of Senescence With Cancer Prognosis and Immunotherapy
por: Zhao, Qinfei, et al.
Publicado: (2022)

Prognostic Inflammasome-Related Signature Construction in Kidney Renal Clear Cell Carcinoma Based on a Pan-Cancer Landscape
por: Zheng, Tianyu, et al.
Publicado: (2020)

Pan-cancer analyses reveal multi-omics and clinical characteristics of RIO kinase 2 in cancer
por: Li, Kexin, et al.
Publicado: (2022)

Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
por: Hao, Yang, et al.
Publicado: (2019)

Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer
por: Yuan, Jing, et al.
Publicado: (2022)

Targeting inflammasome/IL-1 pathways for cancer immunotherapy
por: Guo, Beichu, et al.
Publicado: (2016)

Identification of Claudin-6 as a Molecular Biomarker in Pan-Cancer Through Multiple Omics Integrative Analysis
por: Zhang, Chiyuan, et al.
Publicado: (2021)

Integrated in silico analysis of LRP2 mutations to immunotherapy efficacy in pan-cancer cohort
por: Li, Chunbo, et al.
Publicado: (2022)

An integrated multi-omics analysis of topoisomerase family in pan-cancer: Friend or foe?
por: Zhou, Xin, et al.
Publicado: (2022)

Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data
por: Xu, Yanjun, et al.
Publicado: (2022)

Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
por: Wang, Li-Qiu, et al.
Publicado: (2021)

Roles of AIM2 Gene and AIM2 Inflammasome in the Pathogenesis and Treatment of Psoriasis
por: Wang, Jieyi, et al.
Publicado: (2022)

Multi-omics analysis reveals the panoramic picture of necroptosis-related regulators in pan-cancer
por: Li, Guanghao, et al.
Publicado: (2022)

Immunotherapy in head and neck cancer: aiming at EXTREME precision
por: Szturz, Petr, et al.
Publicado: (2017)

The Role of AIM2 Inflammasome in Knee Osteoarthritis
por: Yang, Jiyong, et al.
Publicado: (2022)

Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis
por: Qin, Yan, et al.
Publicado: (2023)

Genomic investigation of co-targeting tumor immune microenvironment and immune checkpoints in pan-cancer immunotherapy
por: Huang, Xing, et al.
Publicado: (2020)

HILPDA Is a Prognostic Biomarker and Correlates With Macrophage Infiltration in Pan-Cancer
por: Liu, Chengdong, et al.
Publicado: (2021)

A hierarchical spike-and-slab model for pan-cancer survival using pan-omic data
por: Samorodnitsky, Sarah, et al.
Publicado: (2022)

Regulatory Cues in Pulmonary Fibrosis—With Emphasis on the AIM2 Inflammasome
por: Tseng, Yu-Hsin, et al.
Publicado: (2023)

Pan-cancer analyses of pyroptosis with functional implications for prognosis and immunotherapy in cancer
por: Liu, Aibin, et al.
Publicado: (2022)

Identification of Pan-Cancer Prognostic Biomarkers Through Integration of Multi-Omics Data
por: Zhao, Ning, et al.
Publicado: (2020)

I kappa B kinase interacting protein as a promising biomarker in pan-cancer: A multi-omics analysis
por: Bi, Chenyang, et al.
Publicado: (2023)

Pan-cancer analysis from multi-omics data reveals AAMP as an unfavourable prognostic marker
por: Wang, Yang, et al.
Publicado: (2023)

A Pan-Cancer Analysis of Predictive Methylation Signatures of Response to Cancer Immunotherapy
por: Xu, Bingxiang, et al.
Publicado: (2021)

Multi-Omics Analysis Reveals the Pan-Cancer Landscape of Bone Morphogenetic Proteins
por: Luo, Wen-Li, et al.
Publicado: (2020)

Pan-Cancer Analysis of the Characteristics of LY96 in Prognosis and Immunotherapy Across Human Cancer
por: Nie, Kechao, et al.
Publicado: (2022)

Author Correction: Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
por: Wang, Li-Qiu, et al.
Publicado: (2022)

Withdrawal notice to: “Pan-cancer analyses of clinical prognosis, immune infiltration, and immunotherapy efficacy for TRPV family using multi-omics data” [Heliyon 9, (2023) 16897]
por: Shen, Chong, et al.
Publicado: (2023)

AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma
por: Zhou, Houhong, et al.
Publicado: (2022)

Multi-omics analysis of LAMB3 as a potential immunological and biomarker in pan-cancer
por: Wang, Yanghao, et al.
Publicado: (2023)

Integrating single-cell and bulk RNA sequencing to predict prognosis and immunotherapy response in prostate cancer
por: Wen, Xiao Yan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6nnke4ss4ere4da894j1o346pb