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Evolutionary View on Lactate-Dependent Mechanisms of Maintaining Cancer Cell Stemness and Reprimitivization

SIMPLE SUMMARY: For a long-time lactic acid has been considered as a toxic end-product of metabolism that cause different adverse effects. However, in recent decades a plenty of studies has refuted this suggestion and revealed many functions of lactate in living organisms. Lactic acid may be conside...

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Detalles Bibliográficos
Autores principales: Shegay, Petr V., Zabolotneva, Anastasia A., Shatova, Olga P., Shestopalov, Aleksandr V., Kaprin, Andrei D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559641/
https://www.ncbi.nlm.nih.gov/pubmed/36230479
http://dx.doi.org/10.3390/cancers14194552